The Kidney Precision Medicine Project (KPMP) is focused on finding new ways to treat acute kidney injury (AKI) and chronic kidney disease (CKD). We will be obtaining kidney tissues from individuals volunteering to participate in KPMP. The tissue will be analyzed in an effort to redefine kidney disease in molecular terms and identify novel targeted therapies. The network will develop state-of-the-art methods to obtain and analyze these biopsies, linking information on cellular programs with kidney structure. We are also developing the next generation of software tools to visualize and understand the various components of these devastating diseases.